商瑜副教授
邮箱：shangyu@bnu.edu.cn
主页：
Shang Y*, Zhao X, Tian B, Wang Y, Ren F, Jia B, Zhai Y, Chen W, He D, Chang Z: CHIP/Stub1 interacts with eIF5A and mediates its degradation. Cellular signalling 2014, 26(5):1098-1104.(*corresponding author)
Shang Y, Xu X, Duan X, Guo J, Wang Y, Ren F, He D, Chang Z: Hsp70 and Hsp90 oppositely regulate TGF-beta signaling through CHIP/Stub1. Biochemical and biophysical research communications 2014, 446(1):387-392.
Shang Y, Zhao X, Xu X, Xin H, Li X, Zhai Y, He D, Jia B, Chen W, Chang Z: CHIP functions an E3 ubiquitin ligase of Runx1. Biochemical and biophysical research communications 2009, 386(1):242-246.
Li RF#, Shang Y#, Liu D, Ren ZS, Chang Z, Sui SF: Differential ubiquitination of Smad1 mediated by CHIP: implications in the regulation of the bone morphogenetic protein signaling pathway. Journal of molecular biology 2007, 374(3):777-790. (#First author
研究方向为肿瘤细胞生物学及抗癌药物开发等研究。具体研究内容为肿瘤发生发展相关的蛋白质组学研究和蛋白质降解调控因子CHIP在肿瘤发生发展中的作用机制研究。